Variant
Enter a mutation of the model's wild type (T315I, or E255K+T315I for several, WT for the wild type itself), or a full protein sequence in one-letter codes.
Model selection
Choose a public or personal protein fitness model. Predictions are in your assay's units, with a 90% interval and the similarity of the variant to the sequences the model was trained on.
Prediction
Built with ESM. Predictions are generated with ESM C 300M (Cambrian Open License). ESM-2 650M is used under the MIT licence.