Upload 2–200 predicted, designed, or experimental structures (PDB or CIF) of the same protein or complex. Add an optional reference, such as a target or crystal structure, to score every member against it. Select a file to preview it.
Every pair is superimposed by sequence-independent structural alignment and scored by TM-score (the lower of its two length normalizations) and RMSD. Structures within the TM-score threshold of a cluster leader join its cluster; each cluster keeps its medoid as the representative. A threshold of 0.5 groups the same fold; 0.8 and above groups near-identical designs.