Hansen Solubility Parameters

Estimate Hansen δD, δP, and δH from SMILES — published values first, then Stefanis–Panayiotou group contribution — and rank solvents for each solute by HSP distance Ra, RED, and Flory–Huggins χ.
0 solutes × 35 solvents
Estimated minimum cost: $—

Examples

Solutes

Paste solute SMILES (APIs, polymer repeat units, generated hits), one per line, or upload a .smi / .txt file. HSP come from published values when available, otherwise from Stefanis–Panayiotou group contribution.

or drop a file here

Experimental solute HSP

Optional. Enter measured HSP (and sphere radius) for any solute above.

Solvents

Choose solvents to rank against each solute by HSP distance Ra, RED, and Flory–Huggins χ. Every panel solvent has published HSP; add other candidates as SMILES below.

35 / 35 panel solvents selected

Custom solvents

Optional. Solvent SMILES, one per line, ranked alongside the selected panel.

Optional settings

▶

Override the HSP source, sphere radius, Flory–Huggins α, temperature, and how many top solvents to keep.